Bioorganic chemistryBoron CompoundsPhotochemotherapyPhotosensitizing AgentsFemaleBreast Neoplasms
Amphiphilic fluorinated Aza-BODIPY alleviates hypoxia in solid tumors and enhances the photodynamic efficacy for breast cancer.
Lina Deng, Gan Xu, Jian-Yong Liu, Mingdong Huang
Published: 202510.1016/j.bioorg.2025.109101
Abstract
Photodynamic therapy (PDT) is an established modality for tumor treatment due to its high spatiotemporal precision and minimal invasiveness. Its efficacy is limited by tumor hypoxia, a hallmark of the solid tumor microenvironment that promotes malign…
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