Bioorganic chemistryProdrugsAnimalsMiceHydrogen PeroxideHumans
AND-gate fluorescence prodrug of the self-immolative delivery for overcoming multidrug resistance.
Jun Liu, Zhengqin Liu, Yifen Yang, Yanli Long
Published: 202510.1016/j.bioorg.2025.109054
Abstract
The principle goal of clinical tumor treatment is to improve the therapeutic outcomes in the clinic while suppressing undesired side-effects of anticancer drugs. However, its clinical usage of fluorescence prodrug was significantly hampered with some…
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