Biomaterials
Methionine-depleting engineered probiotics promote PD-L1 antibody immunotherapy by activating the STING pathway.
Tiantian Sun, Qiushuang Zhang, Yicong Dai, Yuhan Liu, Xucong Teng, Jinghong Li
Published: 202610.1016/j.biomaterials.2026.124015
Abstract
The metabolic differences between tumor cells and normal tissue cells offer potential targets for therapeutic intervention. For instance, compared to normal tissues, tumor cells exhibit a significantly higher dependency on methionine. However, curren…
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