Biomaterials
Spatiotemporal controls of neutrophil extracellular traps boosts neutrophils immunotherapy efficiency against solid tumors.
Lingxiao Jin, Liang Chen, Yucheng Xue, Keye Chen, Shixin Chen, Kelei Wang, Fangqian Wang, Guoxin Qu, Zhenxuan Shao, Shenzhi Zhao, Haochen Mou, Hao Zhou, Zengjie Zhang, Xiayu Hu, Jiangchu Lei
Published: 202610.1016/j.biomaterials.2026.124012
Abstract
Neutrophils have emerged as promising candidates for next-generation immunotherapies against solid tumors. However, the physical barrier formed by tumor-induced neutrophil extracellular traps (NETs) significantly restricts the migration and infiltrat…
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