Biomaterials
DAT-delivered astaxanthin reprograms adipogenesis through RhoGDI1 dephosphorylation at Ser174 and RhoA/FAK/ERK1/2 cascade suppression.
Yapeng Hou, Yanhui Zhang, Ziyu Ma, Xin Chen, Yuanmao Xiao, Yuxuan Zhong, Fanglin Wang, Hao Tong, Xiaohong Wang, Jun Fan
Published: 202610.1016/j.biomaterials.2026.123979
Abstract
Adipose tissue serves as a primary approach for soft tissue defect repair, but clinical regeneration remains limited by inadequate adipogenic capacity. While astaxanthin (AST) can ameliorate adipose dysfunction, the underlying mechanisms governing it…
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