Biomaterials
Carrier-free nanoassembly with dual antioxidant and anti-inflammatory activities camouflaged by melanoma cell membrane for tau-targeted therapy of Alzheimer's disease.
Rui Xue, Fengyu Wang, Beibei Zhang, Jin Wu, Ningnannan Zhang, Chunyang Sun
Published: 202510.1016/j.biomaterials.2025.123970
Abstract
Targeting phosphorylated tau (p-tau) across the blood-brain barrier (BBB) represents a critical prerequisite for attenuating tau pathology and disease progression in Alzheimer's disease (AD) by alleviating oxidative stress and neuroinflammation. To a…
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