Biomaterials
ROS-triggered transformation of microgels to bioadhesive patch for orally administrated treatment of inflammatory bowel disease.
Yi-Jing Yin, Kuo-Ran Xing, Yu-Tong Li, Fan Jia, Ting Ding, Min-Jie Chen, Tian-Tian Zhang, Jian Ji, Ke-Feng Ren, Cheng-Fu Xu, Jie Zhang
Published: 202510.1016/j.biomaterials.2025.123937
Abstract
Inflammatory bowel diseases (IBD) are driven by excessive reactive oxygen species (ROS) and progressive disruption of the intestinal mucus barrier, yet sustained mucosal protection remains insufficiently addressed by current therapies. Here, we devel…
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