BiomaterialsPhotochemotherapyHumansAnimalsPhotosensitizing AgentsNitroreductases
All-in-one molecular design of activatable phototheranostic platform for potent hypoxia-tolerant photodynamic immunotherapy of cancer.
Jiao Chen, Mengyao She, Xiuying Xie, Zesi Wang, Yudi Cheng, Zihan Zhang, Hui Li, Xi Chen, Ping Liu, Fulin Chen, Shengyong Zhang, Jianli Li
Published: 202610.1016/j.biomaterials.2025.123900
Abstract
Fluorescence imaging-guided photodynamic therapy (PDT) offers immense clinical potential for cancer treatment. However, their therapeutic efficacy and biosafety are compromised by the high oxygen dependency of traditional Type II photosensitizers and…
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