BiomaterialsAnimalsNotochordNucleus PulposusHumansDogs
A bioactive hydrogel harnessing the regenerative potential of notochordal cells serves as instructive cell carrier for nucleus pulposus repair.
Lisanne T Laagland, Elias Salzer, Georgina Targa Fabra, Xiaole Tong, Deepani W L Poramba-Liyanage, Julie Warin, Kieran Joyce, Joseph Snuggs, Frank M Riemers, Lizette Utomo, Seyed A Kamali, Tara C Schmitz, Noemy S Vergara Vera, Christine L Le Maitre, Benjamin Gantenbein
Published: 202610.1016/j.biomaterials.2025.123895
Abstract
Natural biomatrices are popular owing to their ability to mimic tissue-specific biological properties. These properties are crucial for the intervertebral disc, a particularly demanding tissue whose degeneration is a major cause of chronic lower back…
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