BiomaterialsHumansCancer-Associated FibroblastsApoptosisTropomyosinMicroRNAs
Selective killing of cancer-associated fibroblasts by ultrasound-mediated mechanical forces.
Gomathi Sankar, Arka Roy Choudhury, Rashmita Luha, Akshay Kumar, Ketan Kulkarni, Mingxi Yao, Rudra Pratap, Aravind Kapali, Ajay Tijore
Published: 202610.1016/j.biomaterials.2025.123844
Abstract
Recent studies show that stretch/ultrasound (US)-generated mechanical forces cause selective apoptosis in several cancer cells, tumor organoids and animal models without damaging normal cells. Cancer-associated fibroblasts (CAFs) are an integral tumo…
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