BiomaterialsBenzophenonesAnimalsKetonesOsseointegrationPolyethylene Glycols
Novel PEEK fabrication using fused strand deposition reduces inflammation and enhances MSC differentiation promoting bone growth and implant osseointegration.
David Joshua Cohen, Jingyao Deng, Todd M Reith, Eleanor L Sabalewski, Dmitry Pestov, Jonathan T Dillon, Ammar Y Jawad, Paul J Slosar, Kevin T Foley, Randall F Dryer, Timothy D Bassett, Chambliss C Harrod, Brian C Verrelli, Massimo F Bertino, Erik M Erbe
Published: 202610.1016/j.biomaterials.2025.123833
Abstract
Spine fusion devices fabricated from polyether ether ketone (PEEK) using traditional machining or with surface pores created by salt leaching result in a fibrous connective tissue interface. To overcome this limitation, we used fused strand depositio…
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