BiomaterialsAnimalsPeriodontitisPorphyromonas gingivalisHydrogelsMesenchymal Stem Cells
Chaotropic ion-tuned protein/peptide hydrogel with enhanced trans-barrier delivery for effective periodontitis management via pathogen clearance, immunomodulation, and MSC preservation.
Rui Wang, Jianpeng Zhou, Xin Li, Ding Xiong, Dingming Huang, Yu Shi, Zhenming Wang, Ling Ye
Published: 202610.1016/j.biomaterials.2025.123781
Abstract
Periodontitis increases the risk of tooth loss and systemic comorbidities, with anatomical challenges, particularly in narrow periodontal pockets and furcation regions, necessitating advanced drug delivery systems. The keystone pathogen, Porphyromona…
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