BiomaterialsMaleFerroptosisAdenosine TriphosphateAsthenozoospermiaAnimals
Blood-testis barrier-crossing extracellular vesicles for asthenozoospermia therapy via synergistic ATP replenishment and ferroptosis suppression.
Xinghua Yu, Lingan Zeng, Haiyan Chen, Xuemei Dong, Fan Wen, Mingming Wang, Runqi Pan, Yujun Zhang, Wei Zhu, Dingyuan Yan, Dong Wang, Fei Sun
Published: 202610.1016/j.biomaterials.2025.123777
Abstract
Asthenozoospermia, a leading cause of male infertility characterized by impaired sperm motility, poses significant therapeutic challenges due to the restrictive blood-testis barrier (BTB). To address this limitation, we engineered multifunctional ext…
Preview only. Read the full abstract at the source