BiomaterialsHumansTissue EngineeringApoptosisHeart Valve ProsthesisHeart Valves
Apoptosis as a strategy for enhancing decellularization and remodeling of tissue-engineered heart valves.
Pascal Breitenstein, Marcy Martin, Valery L Visser, Sarah E Motta, Maximilian Y Emmert, Melanie Generali, Simon P Hoerstrup
Published: 202610.1016/j.biomaterials.2025.123765
Abstract
In situ tissue-engineered heart valves (TEHVs) using human cell-derived tissue engineered matrices (hTEMs) offer a promising solution to current heart valve prosthesis limitations. Decellularization is crucial for producing hTEMs by removing cellular…
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