BiochimieHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHydroxymethylglutaryl CoA ReductasesPeptidesDrug Design
Design of competitive inhibitory peptides for 3-hydroxy-3-Methylglutaryl coenzyme A reductase.
Valeriy V Pak, Shomansur Sh Sagdullaev, Aleksandr V Pak
Published: 202610.1016/j.biochi.2025.10.017
Abstract
The effectiveness of statins in preventing hypercholesterolemia and associated cardiovascular diseases has been confirmed for a long time. Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR). This enzyme plays…
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