The international journal of biochemistry & cell biologyAnimalsNLR FamilyPyrin Domain-Containing 3 ProteinInflammasomesPaxillin
Paxillin mediates lung epithelial injury by activating NLRP3 inflammasomes in an acute respiratory distress syndrome mouse model.
Honglin Feng, Xinyi Cao, Yong You, Kengliang Rao, Hongjia Chen, Qing Chen, Li Chen
Published: 202610.1016/j.biocel.2025.106880
Abstract
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is a clinical syndrome characterized by diffuse lung inflammation and edema, with diffuse alveolar damage as the hallmark pathology. Paxillin plays a crucial role in the signaling pat…
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