Biomaterials advances
3D printing of Y-27632 enhanced elastic hydrogel conduits for peripheral nerve repair.
Wenbi Wu, Haofan Liu, Jiamei Zhang, Yinchu Dong, Min Peng, Qi Zhu, Yi Zhang, Wei Zhao, Li Zhang, Ya Ren, Jinlu Liu, Boya Li, Wentao Li, Yu Hu, Jingzhu Duan
Published: 202510.1016/j.bioadv.2025.214679
Abstract
Nerve guide conduits provide an advanced tool for peripheral nerve repair, but their efficacy remains limited due to suboptimal axon regeneration. Y-27632, a ROCK inhibitor, has the potential to promote axon regeneration and functional restoration. H…
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