Biomaterials advancesDoxorubicinHydrogelsAnimalsHumansHead and Neck Neoplasms
Localized chemo-immunotherapy for HNSCC via CpG-synergized doxorubicin release from injectable TPGS/Na₂CO₃ hydrogel remodeling tumor immunity.
Chen Wang, Yin Li, Xiaoxue Shen, Shiwei Xiao, Huiying Du, Qianye Zhao, Ying Wang, Qiangtao Zhang, Shuxin Wen
Published: 202610.1016/j.bioadv.2025.214588
Abstract
BACKGROUND: Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) exhibit poor survival due to tumor microenvironment (TME) barriers and systemic toxicity of chemo-immunotherapy associated with chemo-immunotherapy. METHODS: An…
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