Biomaterials advancesOsteosarcomaHumansCeramicsCopperCell Line
Novel Ce/Cu-modified black ceramics disrupted mitochondrial dysfunction and tricarboxylic acid cycle to induce cuproptosis in osteosarcoma cells.
Rongxiang Zhang, Xuelei Yin, Zenghui Xu, Qikang Yan
Published: 202610.1016/j.bioadv.2025.214576
Abstract
PURPOSE: Development of Ce/Cu-modified black ceramics and investigation of the mechanism of anti-osteosarcoma activity. METHODS: Black ceramics doped with 0.3-0.7 wt% CeO2 and CuO were prepared and analyzed using energy-dispersive X-ray spectroscopy…
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