Biochemical pharmacology
Silencing OGFOD1 ameliorates hepatic ischemia-reperfusion injury through abrogating oxidative stress and apoptosis via downregulating SPARC.
Zexin Li, Xiao Wang, Yuanyuan Cui, Yi Liu, Rui Wei, Yixin Wang, Xiaolong Tang, Liangbin Li, Jiasai Li, Keqiang Zuo
Published: 202610.1016/j.bcp.2026.117719
Abstract
Hepatic ischemia-reperfusion injury (HIRI) is a complicated pathological process impacting the prognosis of patients suffering from liver resection and transplantation surgery. 2-oxoglutarate and iron dependent oxygenase domain containing 1 (OGFOD1),…
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