Biochemical pharmacologyHumansCarcinomaHepatocellularSTAT3 Transcription FactorLiver Neoplasms
Ginsenoside Rh3 enhances regorafenib efficacy in hepatocellular carcinoma by modulating FGFR4-STAT3-YAP signaling pathway.
Youngsic Jeon, Hyukjoon Kwon, Jeong Eun Yoo, Keunwan Park, Taek Chung, Young Nyun Park, Jinchan Sim, Taejung Kim, Jungyeob Ham, Young-Joo Kim
Published: 202610.1016/j.bcp.2026.117679
Abstract
Efforts to develop more effective and safer cancer therapies have driven growing interest in combination treatments using well-established agents. Here we investigate whether ginsenoside Rh3, a bioactive constituent of Panax ginseng, enhances the ant…
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