Biochemical pharmacologyInterleukin-15AnimalsHumansInterleukin-7Mice
Enhancement of B7-H3 chimeric antigen receptor-T cell efficacy via the coexistence effect of IL-7, IL-15 and CCL19 for pancreatic and lung xenograft tumors.
Qiong Zhang, Zu-Chian Chiang, Huanjiao Weng, Xinyi Chen, Ningning Zhao, Cailin Yan, Yonglei Xiao, Jizhen Lin, Yunlu Xu
Published: 202610.1016/j.bcp.2026.117673
Abstract
In current clinical applications, there are challenges with using chimeric antigen receptor (CAR)-T cells to effectively treat solid tumors. These challenges include promoting the infiltration and proliferation of CAR-T cells, as well as extending th…
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