Biochemical pharmacologyLipopolysaccharidesAnimalsMiceSolute Carrier Family 12Member 2
Sodium-potassium-chloride cotransporter 1 as a novel regulator of DAMPs-mediated alveolar epithelial-macrophage crosstalk in LPS-induced lung inflammation.
Guan-Ting Liu, Po-Chun Hsieh, Yao-Kuang Wu, Kuo-Liang Huang, Mei-Chen Yang, Wen-Lin Su, Chan-Yen Kuo, Chou-Chin Lan
Published: 202610.1016/j.bcp.2026.117671
Abstract
Sepsis is a life-threatening condition characterized by uncontrolled systemic inflammation, in which macrophages play a pivotal role by releasing proinflammatory cytokines that exacerbate organ dysfunction and mortality. When injured, alveolar epithe…
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