Biochemical pharmacologyHumansSodium-Glucose Transporter 2 InhibitorsGlucosidesPlatelet ActivationBenzhydryl Compounds
Common and distinct effects of sodium-glucose cotransporter-2 inhibitors on in vitro platelet activation.
Surasak Wichaiyo, Rasika Khaeduang, Supavit Taesakul, Noppawan Phumala Morales
Published: 202610.1016/j.bcp.2025.117667
Abstract
Recent studies have demonstrated antiplatelet activity of sodium-glucose cotransporter-2 (SGLT2) inhibitors, particularly at high micromolar concentrations (10-30 µM). However, the effects of clinically relevant nanomolar concentrations on platelet f…
Preview only. Read the full abstract at the source