Biochemical pharmacologyAnimalsFlavonesAtherosclerosisTumor Suppressor Protein p53Humans
Mechanistic insights into acacetin-mediated atherosclerosis suppression: targeting HDAC4/p53-regulated ferroptosis signaling pathway.
Ruiqi Zhao, Qingqing Sun, Shiqi Shan, Huijun Sun, Ciren Baima, Yue Jin
Published: 202610.1016/j.bcp.2025.117664
Abstract
Acacetin, a natural flavonoid compound, exhibits anti-inflammatory, antioxidant, and lipid-lowering properties, indicating promising therapeutic potential for the prevention and treatment of cardiovascular diseases (CVD). However, the mechanisms unde…
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