Biochemical pharmacologyHumansRivaroxabanMaleFemaleMiddle Aged
Inflammatory protein signatures associated with high rivaroxaban exposure.
Catherine Feliu, Jean Escal, Cyril Leven, Sophie Hodin, Vanessa Rigaud, Philippe Gonzalo, Francis Coutureau, Karine Lacut, Jeremy Thereaux, Xavier Delavenne
Published: 202610.1016/j.bcp.2025.117663
Abstract
Direct oral anticoagulants, including rivaroxaban, are widely prescribed for the prevention and treatment of thromboembolic disorders. Despite generally predictable pharmacokinetics (PK), real-world data reveal striking interindividual variability in…
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