Biochemical pharmacologyAnimalsStearoyl-CoA DesaturaseMuscleSmoothVascular
SCD1 deficiency alters the perivascular secretory function of adipocytes and induces phenotypic changes in vascular smooth muscle cells.
Adrian Sowka, Volodymyr V Balatskyi, Viktor O Navrulin, James M Ntambi, Pawel Dobrzyn
Published: 202610.1016/j.bcp.2025.117633
Abstract
Perivascular adipose tissue (PVAT) maintains vascular homeostasis by secreting vasoactive factors that interact with vascular smooth muscle cells (VSMCs). VSMCs maintaining the structure and function of blood vessels through their contractile phenoty…
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