Biochemical pharmacologyProtein-Arginine N-MethyltransferasesHumansPurine-Nucleoside PhosphorylaseNeoplasmsAnimals
Current status and prospects of methylthioadenosine phosphorylase/protein arginine methyltransferase 5 target therapy.
Jing Lin, Huishan Zhang, Hui Kang, Yu Chen
Published: 202610.1016/j.bcp.2025.117561
Abstract
Methylthioadenosine phosphorylase (MTAP) and protein arginine methyltransferase 5 (PRMT5) are two important targets that have attracted much attention in oncology in recent years. The former is involved in methionine metabolism and its absence leads…
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