Biochemical pharmacologyDiabetic NephropathiesMitophagyAnimalsHumansMice
Upregulation of BNIP3 alleviates renal tubular cell injury by activating mitophagy in diabetic nephropathy.
Zi-Yun Hu, Qi-Hang Sun, Yu Ma, Yu-Kai Wang, Chao-Yi Chen, Xin-Ran Liu, Xiao-Han Ma, Xue-Qi Liu
Published: 202610.1016/j.bcp.2025.117440
Abstract
Diabetic nephropathy (DN) leads to significant renal tubular and interstitial damage, yet effective preventive and therapeutic strategies remain scarce. Abnormal mitophagy may contribute to DN progression, but the underlying regulatory mechanisms are…
Preview only. Read the full abstract at the source