Biochemical pharmacologyCarcinomaHepatocellularLiver NeoplasmsHumansExons
Exon 13 skipping mediated by HNRNPL facilitates truncated SLK-induced metastasis in hepatocellular carcinoma.
Zhongxue Guo, Peining Yu, Liu Yu, Mengzhen Huang, Zhiwei Wu, Aime Gael Yaya Traore, Zhen Sun, Ziyou Bai, Wei Wu, Tongzheng Liu, Qiang Li, Feng Wang
Published: 202510.1016/j.bcp.2025.117390
Abstract
The STE20-like serine/threonine-protein kinase (SLK), a key regulator of cellular signaling, exhibits remarkable functional heterogeneity through alternative splicing in various cancers. This study investigates the splicing regulation of SLK in hepat…
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