Biochemical and biophysical research communications
smFASTIA: A high-sensitivity platform for purification-free kinetic screening of protein-small molecule interactions.
Yuki Tokunaga, Ryo Matsunaga, Satoru Nagatoishi, Kouhei Tsumoto
Published: 202610.1016/j.bbrc.2026.153300
Abstract
Elucidating the binding kinetics of protein-small molecule interactions is critical for optimizing drug efficacy and understanding mechanism of action. However, establishing structure-kinetic relationships is often hindered by the throughput of condi…
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