Biochemical and biophysical research communicationsHumansPrecursor B-Cell Lymphoblastic Leukemia-LymphomaMEF2 Transcription FactorsCell LineTumor
Multi-scale transcriptomics analysis reveals MHC suppression in MEF2D fusion positive B-cell acute lymphoblastic leukemia.
Weina Zhang, Yongjing Liu, Xinhua Xiao, Qingqing Zheng, Yali Xie, Jinping Li, Tao Zeng, Yuliang Wang, Hua Jiang, Jinyan Huang
Published: 202610.1016/j.bbrc.2026.153274
Abstract
MEF2D gene related fusions, define a unique B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with poor prognosis. In this study, we performed single-cell RNA sequencing (scRNA-seq) on three MEF2D fusion cases and collected transcriptomic data…
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