Biochemical and biophysical research communicationsHumansLiver NeoplasmsCarcinomaHepatocellularAmino Acid Oxidoreductases
LOXL2 and SYVN1 cooperate across cellular compartments to drive liver hepatocellular carcinoma progression.
Rui Yan, Xiaoli Jiang, Rui Shi, Zhaojie Liu, Wenjing Zhou, Linhai Su, Zihan Wang, Weikang Hu, Qingya He, Jian Zhong, Zhen Yang, Hongmei Bai, Shengquan Zhang, Sumei Zhang
Published: 202610.1016/j.bbrc.2025.153201
Abstract
BACKGROUND: The synergistic interplay between extracellular matrix (ECM) remodeling and proteostatic adaptation in the progression of liver hepatocellular carcinoma (LIHC) remains incompletely characterized. Notably, LOXL2 (a critical regulator of EC…
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