Biochemical and biophysical research communicationsHumansLipopolysaccharides1-(5-Isoquinolinesulfonyl)-2-MethylpiperazineOrganoidsCell Line
Fasudil alleviates lipopolysaccharides-triggered damage to BEAS-2B cells and human lung organoids by inducing CLDN4 expression.
Chenghang Jiang, Liming Xu, Tianpeng Wang, Shengang Zhou, Gaoxiang Li, Yueliang Zheng
Published: 202610.1016/j.bbrc.2025.153178
Abstract
BACKGROUND: Fasudil, a well-known selective ROCK inhibitor, is commonly used to treat cerebral vasospasm. Recent research suggests that Fasudil may also have therapeutic potential for lung conditions such as pulmonary hypertension and acute lung inju…
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