Biochemical and biophysical research communicationsAlzheimer DiseaseHumansSignal TransductionEndoplasmic Reticulum StressEndoribonucleases
Exercise impact on IRE1α signaling: Novel insights into Alzheimer's disease prevention and treatment.
Tu Haixia, Xu Bo
Published: 202610.1016/j.bbrc.2025.153156
Abstract
Endoplasmic reticulum stress (ERS) and its downstream signaling play a central role in neuroinflammation in Alzheimer's disease (AD). Among them, IRE1α, as a key sensor of ER stress, is a pivotal molecule connecting stress to inflammation. Its aberra…
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