Biochemical and biophysical research communicationsProteasome Endopeptidase ComplexAdipocytesAnimalsMiceProteolysis
SPSB proteins regulate adipocyte differentiation by targeting FOG-2 for proteasomal degradation.
Yuka Sugiya, Ken Maruyama, Honoka Suzuki, Reina Miyashita, Takashi Uehara, Tadashi Nishiya
Published: 202610.1016/j.bbrc.2025.153147
Abstract
Friend of GATA (FOG)-2 is a transcriptional cofactor that cooperates with GATA family transcription factors to regulate the development of multiple organs and tissues. During adipocyte differentiation, FOG-2 protein is rapidly downregulated, and this…
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