Biochemical and biophysical research communicationsCarcinomaHepatocellularLiver NeoplasmsHumansAnimals
TARDBP upregulates GJB2 to promote tumor progression in hepatocellular carcinoma.
Yuhong Zhu, Mingchao Hu, Rongcan Xu, Jinlong Zhai, Linlin Yang, Xingtao Jin
Published: 202610.1016/j.bbrc.2025.153123
Abstract
BACKGROUND: TAR DNA-binding protein (TARDBP), an RNA-binding protein (RBP), plays a crucial role in regulating mRNA stability. However, its involvement in hepatocellular carcinoma (HCC) pathogenesis and immune evasion, through regulating gap junction…
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