Biochemical and biophysical research communicationsAnimalsGlucagon-Like Peptide 1Mesenchymal Stem CellsInsulin-Secreting CellsDiabetes Mellitus
Engineered MSCs secreting GLP-1 enhance β-cell survival and improve glycemic control in diabetic mice.
Zheng Huang, Yuyi Zhang, Jingwen Tian, Pengbo Song, Cailing Tong, Zhongquan Qi
Published: 202610.1016/j.bbrc.2025.153105
Abstract
Type 1 diabetes (T1D) arises from autoimmune destruction of pancreatic β-cells, leading to insufficient insulin production and impaired glucose regulation. Although insulin therapy and islet transplantation remain the primary treatment options, both…
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