Biochemical and biophysical research communicationsAnimalsTriterpenesDynaminsRatsSprague-Dawley
The role and mechanism of asiaticoside in regulating smooth muscle cell mitochondrial Drp1 during neointimal hyperplasia and atherosclerosis.
Mingyu Liu, Lu Wang, Lina Wang, Tao Yang, Fei Xiang, Junyao Lu, Sixuan Chen, Hui Li, Yaxin He, Wei Wang, Shuyuan Guo, Yuanyuan Guo
Published: 202610.1016/j.bbrc.2025.153102
Abstract
Early atherosclerosis is characterized by aberrant proliferation and migration of vascular smooth muscle cells (VSMCs). Asiaticoside (ASI), the primary bioactive constituent of Centella asiatica, has been demonstrated to possess anti-inflammatory and…
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