Biochemical and biophysical research communicationsLysineGlucuronosyltransferaseHumansUDP-Glucuronosyltransferase 1A9Cytoplasm
UDP-glucuronosyltransferase 1A9 function is mediated by the two C-terminal lysine residues and proper mobility/flexibility of the cytoplasmic tail.
Yuu Miyauchi, Yume Sadato, Madoka Sawai, Shinji Takechi, Masahiro Hiratsuka, Peter I Mackenzie, Yuji Ishii
Published: 202610.1016/j.bbrc.2025.153004
Abstract
UDP-glucuronosyltransferase (UGT) is a type-I membrane protein that is localized to the endoplasmic reticulum (ER). The main body of the UGT is located on the luminal side of the ER, whereas a single transmembrane helix, followed by the cytoplasmic t…
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