Biochemical and biophysical research communicationsHydroxymethylglutaryl CoA ReductasesHumansOsteoarthritisCholesterolHydroxymethylglutaryl-CoA Reductase Inhibitors
HMGCR-driven cholesterol metabolism dysregulation and its role in osteoarthritis diagnosis and immune regulation.
Baochen Tao, Jin Zhang
Published: 202510.1016/j.bbrc.2025.152958
Abstract
Osteoarthritis (OA) is the most common degenerative joint disease, and the complexity of its molecular mechanisms has hindered the development of effective diagnostic and therapeutic strategies. In this study, we integrated five independent OA RNA-se…
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