Biochemical and biophysical research communicationsKlebsiella pneumoniaeRifaximinDrug RepositioningAnti-Bacterial AgentsMolecular Docking Simulation
Repurposing rifaximin against Klebsiella pneumoniae via targeting of transcription anti-termination protein RfaH for novel antimicrobial development.
Anam Ashraf, Arunabh Choudhury, Mohammad Ali Khan, Bader S Alotaibi, Saba Noor, Md Imtaiyaz Hassan
Published: 202510.1016/j.bbrc.2025.152954
Abstract
BACKGROUND: Multidrug-resistant Klebsiella pneumoniae (MDR-KP) has become a critical global health threat, challenging the management of infectious diseases. Anti-termination protein RfaH is crucial in promoting virulence across Gram-negative pathoge…
Preview only. Read the full abstract at the source