Biochemical and biophysical research communicationsAnimalsDermatitisAllergic Contact3-Hydroxybutyric AcidAMP-Activated Protein Kinases
Topical β-hydroxybutyrate suppresses allergic dermatitis via HCAR2-CaMKK-AMPK-mediated barrier protection.
Yukihiro Yoshimura, Aya Fujii
Published: 202510.1016/j.bbrc.2025.152931
Abstract
Ketone bodies, particularly β-hydroxybutyrate (BHB), have attracted attention for their anti-inflammatory and immunomodulatory properties. We previously demonstrated that nutritional interventions elevating circulating BHB levels suppress immediate-t…
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