Behavioural brain researchAnimalsBerberineMaleRatsStress
Chronic administration of berberine attenuates depressive-like behavior in rats subjected to chronic unpredictable mild stress combined with ACTH treatment: Role of nitrergic system.
Sharvari Deshmukh, Biru B Dudhabhate, Dipak K Sahare, Dadasaheb M Kokare, Yashashree A Gadhikar
Published: 202610.1016/j.bbr.2025.116006
Abstract
Major depressive disorder (MDD) remains a significant clinical concern because of its poor response to conventional antidepressants. Berberine, an isoquinoline alkaloid of natural origin has shown promising antidepressant-like effects in preclinical…
Preview only. Read the full abstract at the source