Brain, behavior, and immunity
Inhibition of the NFATc2/FKBP5 axis alleviates microglial neuroinflammation by regulating arachidonic acid metabolism in Parkinson's disease.
Yao Si, Xue Zhao, Lei Wu, Xueying Li, Pusheng Quan, Shi Yan, Xinyu Zhang, Lige Han, Lifen Yao, Fan Yang
Published: 202610.1016/j.bbi.2026.106296
Abstract
Microglia-induced neuroinflammation is among the core pathological hallmarks of Parkinson's disease (PD). FKBP5, which has been implicated in stress-related disorders, is recognized as a key regulator of inflammatory responses. However, the role and…
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