Brain, behavior, and immunityAnimalsZebrafishPorphyromonas gingivalisGingipain Cysteine EndopeptidasesLarva
Porphyromonas gingivalis induces neuroinflammation in a gingipain-dependent manner in zebrafish larvae.
Magdalena Widziolek, Anna Mieszkowska, Magdalena Marcinkowska, Aleksandra Domagalska, Maria Zawisza, Zbigniew Soltys, Jan Potempa, Magdalena Chadzinska
Published: 202610.1016/j.bbi.2025.106234
Abstract
Porphyromonas gingivalis (Pg), a keystone pathogen in the development of periodontitis, has been implicated in neurodegenerative diseases such as Alzheimer's disease (AD). The gingipains, Pg crucial virulence factors, have been detected in the brains…
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