Brain, behavior, and immunityAnimalsBortezomibGangliaSpinalMale
Targeting sex-specific DRG inflammation and neurofibrosis to prevent Bortezomib-induced neuropathy.
Michael B Thomsen, Abhishek Singh, Christina N Thebeau, Vivian D Gao, Nicholas F Schulze, Shannon M Landon, Oshri Avraham, Sarah X Yang, Shriya Koneru, Sami S Geier, Aidan Pelea, Valeria Cavalli, Stefanie Geisler
Published: 202510.1016/j.bbi.2025.106124
Abstract
Peripheral neuropathy is a common and often debilitating side effect of the chemotherapeutic agent bortezomib (BTZ), yet its mechanisms remain incompletely understood. To investigate the pathogenesis of BTZ-induced peripheral neuropathy (BIPN), we de…
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