Biochimica et biophysica acta. Reviews on cancerHumansUbiquitinsNeoplasmsCytokinesAnimals
The multifaceted roles of ISG15 in cancer: Conjugated and free forms.
Xinran Liu, Qiujin Ma, Zhao Jia, Churong Zou, Kun Huang
Published: 202510.1016/j.bbcan.2025.189473
Abstract
Interferon-stimulated gene product 15 (ISG15) is a ubiquitin-like protein. It functions as a conjugated form by covalently modifying target proteins (ISGylation), or in a free form, both are involved in a broad variety of cellular processes. Increasi…
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