Biochimica et biophysica acta. Reviews on cancerAnimalsHumansDrug DevelopmentAntineoplastic AgentsNeoplasms
Advancing oncology drug development: Innovative approaches to enhance success rates while reducing animal testing.
Hans Hendriks
Published: 202510.1016/j.bbcan.2025.189467
Abstract
Drug development remains a high-risk endeavour, particularly in oncology, where failure rates exceed 90 %. This review examines emerging tools and strategies designed to enhance preclinical success rates, aligning with the 3Rs principle: Reduction, R…
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