Biochimica et biophysica acta. Proteins and proteomicsForkhead Transcription FactorsPAX6 Transcription FactorHumansAutism Spectrum DisorderDNA
Novel interactions between FOXP2 and PAX6: Implications for neural development and autism spectrum disorders.
Jessica Brothwell, Olamide Jeje, Dineo Mashamaite, Sylvia Fanucchi
Published: 202610.1016/j.bbapap.2025.141110
Abstract
FOXP2 and PAX6 are transcription factors essential for neural development, with mutations in both linked to autism spectrum disorders (ASDs). Their DNA-binding domains include a forkhead domain (FHD) for FOXP2 and a paired domain (PD) plus homeodomai…
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